The Words of God are the most important words there are.

But he answered and said, It is written, Man shall not live by bread alone, but by every word that proceedeth out of the mouth of God.

Matthew 4:4

Reading this, we must consider every word in the Bible as significant. That doesn't mean we should take partial verses out of context and bend the meaning to fit anything that comes to mind. However, we should observe each word of each sentence with the reverence that is merited it's Originator.

Based on Matthew 5:18, we can see that the parts of each word are important.

For verily I say unto you, Till heaven and earth pass, one jot or one tittle shall in no wise pass from the law, till all be fulfilled.

Matthew 5:18

The words "Jot" and "Tittle" are Hebrew terms of which you may be unfamiliar. Here, Dr. Charles Ryrie gives a very good explanation as to what the words mean. He also makes a pertinent comment on the preceding verse.

A jot is the Hebrew letter yod, the smallest letter in that alphabet. It looks much like an English apostrophe. The word tittle means a minor stroke and refers to the almost unnoticeable strokes which distinguish certain Hebrew letters from others. For instance, the tittle that differentiates a d (daleth) from an r (resh) is a protrusion that in a normal font of type would not be more than a 1/16 of an inch. Of course the presence or absence of the tittle could change the spelling of a word and likely change the meaning. The Lord was emphasizing that every letter of every word is important, and what those words say in sentences and paragraphs is completely accurate. In fact, they can be depended on to be fulfilled exactly as spelled out letter by letter and word by word in all the promises of the Old Testament.

- Charles Ryrie, The Bible Truth Without Error (booklet, revised edition 1977), page 7

One should not simply gloss over passages in the Bible. Each book, each chapter, sentence, word, and part of each word should be read and understood in the context that was intended. I don't know of anyone who can absorb it all in one reading. For this reason, the Bible should be read repeatedly.